Often people with depression or other mental health disorders demonstrate an abnormal production of a group of chemicals called 'pyrroles', this is called pyroluria. The pyrroles rob the body of B6 and Zinc causing them to be excreted in the urine. This may result in a deficiency of B6 and zinc, which supplementation can correct. It is most often seen in females. It is thought that about 10% of a normal population has pyroluria, which may cause symptoms when the patient is stressed
Signs and symptoms of pyroluria are many. There seems to be a familial or genetic component. A family history of mental illness and all-girl families especially if there is also a history of miscarried boys.
" Frequent ear infections as a child, as well as colds, fevers and chills.
" Nervous exhaustion
" Poor memory or inability to think clearly
" Mood swings
" Lack of regular periods in girls
" Impotence in males
" Unusual smelling breath and body odour
" Inability to tolerate drugs and alcohol
" Cold hands and feet
" Abdominal pain
" Intolerance to some protein foods, drugs or alcohol
" Morning nausea and constipation
" Difficulty remembering dreams
" Frequent head colds and infections
" Stretch marks in the skin
Pyrolurics can often be identified by their appearance:
" Pale skin. A black pyroluric will have the lightest skin in the family
" A lack of hair on the head, eye brows and eye lashes
" Teeth in the upper jaw will often be overcrowded (unless orthodontic treatments has taken place). and poor appearance of tooth enamel.
" White marks on fingernails, be opaque and be tissue paper thin.
" Acne, eczema, and herpes may also be present.
Pyroluria can occur at any age but appears to be brought on by stress. It is familial and may be a factor in the development of mental retardation, epilepsy, hyper activity and particularly depression.
What does the test involve?
Morning spot urine specimen - in urine jar (with Ascorbate as a long term preservative-optional).
Note: Even without Ascorbate the results are accurate and reproducible for up to 7 days.